ICU sedation, delirium & recovery
The Effect of Sleep Disorder Interventions in Patients With Obstructive Sleep Apnea Undergoing Solid-Organ Transplants: A Systematic Review
Study context
- Population
- Adults (≥18 years) with obstructive sleep apnea (OSA) undergoing solid-organ transplantation3 studies
- Comparison
- OSA therapies such as continuous positive airway pressure (CPAP) in solid-organ transplant
- Outcome
- Sleep parameters (1 study, heart transplant)
Methodological detailsPRISMA-reported, 1407 studies identified, 38 full-text reviewed, 3 eligible
- PRISMA-reported
- 1407 studies identified, 38 full-text reviewed, 3 eligible
Pooled result
As reported in the abstract
- Nasal CPAP led to significant improvements in Apnea-Hypopnea Index, Arousal Index, and total sleep time with SpO2 <90%
Further pooled results
Graft dysfunction
- Untreated OSA more likely to develop graft dysfunction earlier than treated or no OSA
1-year mortality and 5-year overall survival
- No detectable impact of CPAP after adjustment
Original publication
The Effect of Sleep Disorder Interventions in Patients With Obstructive Sleep Apnea Undergoing Solid-Organ Transplants: A Systematic Review. Anesth Analg. Published 8 August 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →