Neuroanesthesia & neurocritical care
On the utility of near-infrared spectroscopy-derived measures for assessing cerebrovascular autoregulation: results from an observational cohort study
Authors' conclusion
NIRS derived haemoglobin metrics reliably capture slow-wave dynamics reflective of cerebrovascular autoregulation and reactivity, offering a non-invasive alternative to traditional methods.
Study context
- Population
- Moderate to severe traumatic brain injury (TBI) patients with simultaneous near-infrared spectroscopy (NIRS), intracranial pressure (ICP), flow velocity (FV) and arterial blood pressure (ABP) monitoring89 recordings, 412 h
- Participants
- 35 participants
- Exposure
- Haemoglobin-based NIRS metrics vs rSO2
- Outcome
- Coherence, gain and Granger causality between physiological inputs (ABP, FV, ICP) and NIRS outputs, focus on 0.005-0.05 Hz
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
- rSO2 showed poor coherence and low causality, especially with ABP
- Haemoglobin-based NIRS metrics vs rSO2: P < 0.001
Observational data: associations, not effects.
Original publication
On the utility of near-infrared spectroscopy-derived measures for assessing cerebrovascular autoregulation: results from an observational cohort study. J Clin Monit Comput. Published 15 December 2025. doi:10.
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