Neuroanesthesia & neurocritical care

Determination of Cerebral Autoregulation at the Bedside: A Narrative Review

Crit Care MedPublished Narrative review

Authors' conclusion

Bedside CAR monitoring represents a promising approach for personalizing hemodynamic management in critically ill patients.

Study context

Population
Critically ill patients with acute brain injury or systemic critical illness
Comparison
Transcranial Doppler vs Near-infrared spectroscopy vs Intracranial pressure monitoring
Outcome
Bedside CAR monitoring approaches
Methodological detailsSearch of Ovid MEDLINE, PubMed and Cochrane library; original research, reviews, commentaries and guidelines included
  • Search of Ovid MEDLINE, PubMed and Cochrane library; original research, reviews, commentaries and guidelines included

Main finding

As reported in the abstract

  • 3 commonly used bedside approaches for assessing cerebral autoregulation (CAR) identified
  • CAR impairment common across critical illness (acute brain injury, sepsis, cardiac surgery, hepatic failure); dysregulation can lead to secondary brain injury and worse outcomes
  • Techniques vary in invasiveness, continuous monitoring capability and technical requirements
  • Methods can help detect impaired CAR, identify optimal perfusion targets, and may guide individualized management

Original publication

Determination of Cerebral Autoregulation at the Bedside: A Narrative Review. Crit Care Med. Published 19 August 2025. doi:10.1097/ccm.0000000000006790

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