Pediatric anesthesia & critical care
Opioid Administration and Reduction of Pediatric Ileocolic Intussusception
Primary result · Failed reductionResult — go to the resultOdds ratio 0.66 95% CI 0.36–1.22Authors' conclusion
In this cross-sectional study of pediatric ileocolic intussusception, fentanyl administration prior to attempted reduction was not associated with failed reduction.
Study context
- Population
- Children 4 to 48 months with ileocolic intussusception undergoing attempted reduction, 2017–2019median age 17 months
- Participants
- 3,184 children
- Comparison
- Fentanyl vs no fentanyl before attempted reduction
- Fentanyln = 116
- Primary endpoint
- Percentage of patients with failed reduction of ileocolic intussusception
Methodological detailsmulticentre, 86 pediatric tertiary care centers in 14 countries, consecutive sample, Fentanyl given to 116 of 3167 patients (3.66%)
- Multicentre
- 86 pediatric tertiary care centers in 14 countries
- Consecutive sample
- Fentanyl given to 116 of 3167 patients (3.66%)
Primary result
Failed reduction
Odds ratio
0.66
95% CI 0.36–1.22
Fentanyl vs No fentanyl
OR 0.66 (95% CI 0.36–1.22)
As reported in the abstract
- Failed reduction, all patients (484 of 3184)
- 15.20%
Further findings
Factors associated with failed reduction (adjusted analysis)
- Preexisting gastrointestinal anomalies, OR
- 4.38 (95% CI 1.50-12.76)
- Longer triage to reduction time, OR
- 1.04 (95% CI 1.01-1.07)
- Younger age, OR
- 0.96 (95% CI 0.95-0.97)
Original publication
Opioid Administration and Reduction of Pediatric Ileocolic Intussusception. JAMA Netw Open. Published 2 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →