Pediatric anesthesia & critical care

Reduction of Anesthesiologists' Sevoflurane Exposure During Pediatric Mask Induction With an Additional Scavenger: A Randomized Study

Paediatr AnaesthPublished Randomised controlled trial

Primary result · Urinary HFIP concentrationResult — go to the resultCohen's d 3.19

Authors' conclusion

Use of an additional external scavenging system during pediatric mask induction was associated with a substantial reduction in anesthesiologists' biological exposure to sevoflurane, as assessed by urinary HFIP.

Study context

Population
Anesthesiologists performing pediatric mask inductions with sevoflurane in an induction anesthesia room
Participants
20 anesthesiologists
Comparison
Without scavenger vs Scavenger
Primary endpoint
Urinary HFIP (sevoflurane metabolite) concentration, normalized to creatinine
Follow-up
Following morning
Methodological detailsprospective, parallel-group
  • Prospective
  • Parallel-group

Primary result

Urinary HFIP concentration

Cohen's d

3.19

P = 0.002

By group

As reported in the abstract

Original publication

Reduction of Anesthesiologists' Sevoflurane Exposure During Pediatric Mask Induction With an Additional Scavenger: A Randomized Study. Paediatr Anaesth. Published 6 May 2026. doi:10.1002/pan.70205

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