Cardiac arrest & resuscitation

Optic Nerve Sheath Diameter for Assessing Prognosis after Out-of-Hospital Cardiac Arrest

J Crit CarePublished Prospective observational study

Authors' conclusion

CT diagnostics, in particular GWRBG and GWRCBR, as well as NSE as laboratory biomarker, appear as excellent outcome predictors.

Study context

Population
Patients after successful resuscitation from OHCA, December 2017–August 2021
Exposure
Sonographic and computed tomography (CT) ONSD/ONPD vs grey-to-white ratio and laboratory biomarkers (lactate, neuron specific enolase (NSE)) for prognosis
Outcome
Prognostic value for survival and neurological outcome

Main finding

As reported in the abstract

Sonographic ONSD and ONPD: no significant difference between survival and non-survival
p values ≥0.4
CT ONSD, GWRBG, GWRCBR and NSE differed significantly by survival
p values ≤0.005
CT ONSD, GWRBG, GWRCBR and NSE differed significantly by neurological outcome
p values ≤0.04

Observational data: associations, not effects.

Original publication

Optic Nerve Sheath Diameter for Assessing Prognosis after Out-of-Hospital Cardiac Arrest. J Crit Care. Published 8 November 2023. doi:10.1016/j.jcrc.2023.154464

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