Cardiac arrest & resuscitation
Optic Nerve Sheath Diameter for Assessing Prognosis after Out-of-Hospital Cardiac Arrest
Authors' conclusion
CT diagnostics, in particular GWRBG and GWRCBR, as well as NSE as laboratory biomarker, appear as excellent outcome predictors.
Study context
- Population
- Patients after successful resuscitation from OHCA, December 2017–August 2021
- Exposure
- Sonographic and computed tomography (CT) ONSD/ONPD vs grey-to-white ratio and laboratory biomarkers (lactate, neuron specific enolase (NSE)) for prognosis
- Outcome
- Prognostic value for survival and neurological outcome
Main finding
As reported in the abstract
- Sonographic ONSD and ONPD: no significant difference between survival and non-survival
- p values ≥0.4
- CT ONSD, GWRBG, GWRCBR and NSE differed significantly by survival
- p values ≤0.005
- CT ONSD, GWRBG, GWRCBR and NSE differed significantly by neurological outcome
- p values ≤0.04
Observational data: associations, not effects.
Original publication
Optic Nerve Sheath Diameter for Assessing Prognosis after Out-of-Hospital Cardiac Arrest. J Crit Care. Published 8 November 2023. doi:10. 1016/ j. jcrc. 2023. 154464
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