Pediatric anesthesia & critical care
Outcome following anaesthesia in infancy in the Nordic countries: Subgroup analysis of the NECTARINE study
Authors' conclusion
Thirty-day morbidity and mortality data in the Nordic countries did not differ from the overall European cohort.
Study context
- Population
- Infants up to 60 weeks postmenstrual age (PMA) undergoing anaesthesia for surgical or non-surgical procedures in 11 Nordic centres
- Participants
- 447 participants · 530 procedures
- Comparison
- Nordic cohort vs overall European NECTARINE cohort
- Nordicn = 447
- Primary endpoint
- Perioperative critical events requiring intervention
Methodological detailssubgroup analysis, multicentre
- Subgroup analysis
- Multicentre
Primary result
As reported in the abstract
Perioperative critical events triggering interventions
Perioperative critical events triggering interventions, Nordic cohort (cases)
228 of 530
43%
Further findings
Hypotension and hypoxaemia
- Hypotension
- 12.6%
- Hypoxaemia
- 11.7%
- More common in younger patients and those with co-morbidities
Hypo/hypercapnia
- Hypocapnia (cases)
- 1.5%
- Hypercapnia (cases)
- 4.7%
More than two intubation attempts
- Infants requiring >2 intubation attempts (max three)
- 13 (2.9%)
Postoperative ICU admission
- Admitted to postoperative ICU
- 236/530 (44.5%)
Hospital re-admissions · up to 90 days
- Hospital re-admissions
- 98/447 = 21.9%
ASA physical status
- ASA > 2; distribution similar to total European cohort
- 40%
Morbidity and mortality · 30 days
- 30-day morbidity (complications)
- 87/447 = 19.5%
- 30-day mortality
- 8/447, 1.8%
- Did not differ from the overall European cohort
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Outcome following anaesthesia in infancy in the Nordic countries: Subgroup analysis of the NECTARINE study. Acta Anaesthesiol Scand. Published 27 March 2023. doi:10. 1111/ aas. 14236
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