Cardiac arrest & resuscitation

Outcome prediction in comatose cardiac arrest patients with initial shockable and non‐shockable rhythms

Acta Anaesthesiol ScandPublished Prognostic accuracy study

Authors' conclusion

Outcome prediction accuracy was comparable for shockable and non-shockable rhythms.

Study context

Population
Comatose out-of-hospital cardiac arrest (OHCA) survivors still comatose 72 h post-arrest
Participants
128 vs 50
Comparison
Shockable vs non-shockable initial rhythms
  • Shockablen = 128
  • Non-shockablen = 50
Outcome
Accuracy of outcome predictors (FPR for poor, sensitivity for good outcome; good outcome = cerebral performance category 1-2)
Follow-up
Within 6 months
Methodological detailsobservational NORCAST sub-study, stratified by initial rhythm
  • Observational NORCAST sub-study
  • Stratified by initial rhythm

Performance

As reported in the abstract

Outcome prediction accuracy

Good outcome: clinical predictors, SSEP and CT sensitivity in both groups

86%-100%

Neuron-specific enolase (NSE) sensitivity for good outcome 24-72 h post-arrest

22% to 69%

Further findings

Good outcome (cerebral performance category 1-2) · within 6 months

P < 0.001

Original publication

Outcome prediction in comatose cardiac arrest patients with initial shockable and non‐shockable rhythms. Acta Anaesthesiol Scand. Published 24 October 2023. doi:10.1111/aas.14337

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