ICU sedation, delirium & recovery

Outcome, Process, Utilization, and Cost Measurements of Patients Admitted to the ICU in Hospitals With Vs. Without an Intermediate Care Unit: A Nationwide Inpatient Database Study

Crit Care MedPublished Retrospective cohort study

Authors' conclusion

The presence of an IMCU in ICU-equipped hospitals was associated with improved patient outcomes and more efficient ICU utilization, with only modest increase in hospitalization costs.

Study context

Population
Adults admitted to the ICU in Japanese acute-care hospitals (Diagnosis Procedure Combination database), April 2016–March 2023
Participants
2,278,521 adults · 557 hospitals
Exposure
ICU admission to hospitals with vs without an intermediate care unit (IMCU)
  • With IMCUn = 1,771,000
Outcome
Patient-level outcomes
Methodological detailsnationwide, inpatient database
  • Nationwide
  • Inpatient database

Main finding

As reported in the abstract

With IMCU vs Without IMCUEstimate (95% CI)
In-hospital mortality
aOR 0.94(0.89–0.99)
ICU mortality
aOR 0.87(0.83–0.92)
ICU readmission
aOR 0.92(0.85–1.00)
ICU LOS
adjusted rate ratio 0.98(0.98–0.99)

Observational data: associations, not effects.

Further findings

OutcomeMean difference (%) (95% CI)
Hospital-level utilization and costsWith IMCU vs Without IMCU · ICU bed occupancy · cluster-average treatment effect5.5 (3.3–7.7%)
OutcomeEstimate
Hospital-level utilization and costsWith IMCU vs Without IMCU · occupancy for life-sustaining therapies · cluster-average treatment effect8.6 % (95% CI 7.7–9.5%)
Hospital-level utilization and costsWith IMCU vs Without IMCU · reimbursement rates · cluster-average treatment effect5.4 % (95% CI 4.0–6.8%)
Hospital-level utilization and costsWith IMCU vs Without IMCU · annual revenue per ICU bed · cluster-average treatment effect25 million JPY (95% CI 19-31 million JPY)

Transfer between ICU and IMCU

Patients transferred between ICU and IMCU, large variability between hospitals
14.3%

Original publication

Outcome, Process, Utilization, and Cost Measurements of Patients Admitted to the ICU in Hospitals With Vs. Without an Intermediate Care Unit: A Nationwide Inpatient Database Study. Crit Care Med. Published 11 November 2025. doi:10.1097/ccm.0000000000006962

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