Cardiac arrest & resuscitation
Outcomes after decrease in hypothermia usage for out of Hospital Cardiac arrest after targeted temperature management study
Main finding · Favorable CPC outcome at hospital dischargeResult — go to the resultOdds ratio 2.4 CI 1.3–4.6Authors' conclusion
Out of hospital cardiac arrest patients with persistent comatose state treated with hypothermia of 33 °C had improved odds of discharge with good neurologic outcomes when compared to those treated with targeted normothermia.
Study context
- Population
- Adult non-traumatic OHCA patients with persistent comatose state treated with active targeted temperature management, single tertiary academic community hospital, January 2010–December 2019
- Participants
- 634 patients
- Exposure
- Hypothermia 33 °C vs targeted normothermia 36.5 °C
- T33n = 473
- T36.5n = 161reference
- Outcome
- Cerebral Performance Category (CPC) 1 or 2 (good outcome)
- Follow-up
- Hospital discharge
Methodological detailssingle-centre
- Single-centre
Main finding
Favorable CPC outcome at hospital discharge
Odds ratio
2.4
CI 1.3–4.6
P = 0.006
T33 vs T36.5
OR 2.4 (CI 1.3–4.6); P = 0.006
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
| Outcome | OR | P value |
|---|---|---|
| CPC, initial non-shockable rhythm (subgroup) | 2.5 | P = 0.04 |
Cerebral Performance Category (CPC), shockable rhythm (subgroup)
- Improvement not maintained in the shockable rhythm group
Hospital LOS
- Shorter LOS in T33
Mortality, ICU days, ventilator days
- Did not differ between the groups
Original publication
Outcomes after decrease in hypothermia usage for out of Hospital Cardiac arrest after targeted temperature management study. J Clin Monit Comput. Published 8 July 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →