Outcomes with intrathecal 2-chloroprocaine 3% 60 mg and fentanyl 15 μg for cervical cerclage: a retrospective quality assurance study (2021 – 2023)
Authors' conclusion
Intrathecal 2-chloroprocaine 3% 60 mg with fentanyl showed fewer anesthetic failures (but this was not statistically significant) and a modestly longer discharge time than 50 mg.
Study context
- Population
- Patients undergoing transvaginal cervical cerclage with spinal anaesthesia
- Participants
- 208 patients
- Exposure
- Intrathecal 2-chloroprocaine 3% 60 mg vs prior 50 mg cohort
- 60 mgn = 208
- Outcome
- Anesthetic supplementation
Methodological detailsretrospective chart review, historical comparison with prior 50 mg cohort
- Retrospective chart review
- Historical comparison with prior 50 mg cohort
Main finding
As reported in the abstract
P = 0.104
- None required GA
- 0
Observational data: associations, not effects.
Further findings
- Median surgery duration (all included patients)
- 17 [11-25] min
Safety
Postoperative concerns at POD 1 phone call · postoperative day 1
- Transient neurologic symptoms, difficulty ambulating, or voiding
- 0
- Back pain
- 1
- Abdominal discomfort
- 3
- n=122, available from July 2022
Original publication
Outcomes with intrathecal 2-chloroprocaine 3% 60 mg and fentanyl 15 μg for cervical cerclage: a retrospective quality assurance study (2021 – 2023). Int J Obstet Anesth. Published 22 October 2025. doi:10.
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