Oxygenation During Venoarterial Extracorporeal Membrane Oxygenation: Physiology, Current Evidence, and a Pragmatic Approach to Oxygen Titration
Authors' conclusion
Hyperoxia results from a range of ECMO circuit and patient-related factors. It is common during peripheral venoarterial ECMO, and its presence is associated with poor outcome.
Study context
- Population
- Patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (ECMO)
- Outcome
- Oxygenation and hyperoxia during venoarterial ECMO
Methodological detailsSearches of PubMed, SCOPUS, Medline and Google Scholar; observational and interventional studies plus Extracorporeal Life Support Organization guidelines
- Searches of PubMed, SCOPUS, Medline and Google Scholar; observational and interventional studies plus Extracorporeal Life Support Organization guidelines
Main finding
As reported in the abstract
Severe hyperoxia (PaO2 > 300 mm Hg) common
20%
Original publication
Oxygenation During Venoarterial Extracorporeal Membrane Oxygenation: Physiology, Current Evidence, and a Pragmatic Approach to Oxygen Titration. Crit Care Med. Published 7 December 2023. doi:10. 1097/ ccm. 0000000000006134
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