Organ support & nutrition

Oxygenation During Venoarterial Extracorporeal Membrane Oxygenation: Physiology, Current Evidence, and a Pragmatic Approach to Oxygen Titration

Crit Care MedPublished Narrative review

Authors' conclusion

Hyperoxia results from a range of ECMO circuit and patient-related factors. It is common during peripheral venoarterial ECMO, and its presence is associated with poor outcome.

Study context

Population
Patients undergoing peripheral venoarterial extracorporeal membrane oxygenation (ECMO)
Outcome
Oxygenation and hyperoxia during venoarterial ECMO
Methodological detailsSearches of PubMed, SCOPUS, Medline and Google Scholar; observational and interventional studies plus Extracorporeal Life Support Organization guidelines
  • Searches of PubMed, SCOPUS, Medline and Google Scholar; observational and interventional studies plus Extracorporeal Life Support Organization guidelines

Main finding

As reported in the abstract

Severe hyperoxia (PaO2 > 300 mm Hg) common

20%

Original publication

Oxygenation During Venoarterial Extracorporeal Membrane Oxygenation: Physiology, Current Evidence, and a Pragmatic Approach to Oxygen Titration. Crit Care Med. Published 7 December 2023. doi:10.1097/ccm.0000000000006134

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