Pain treatment after total hip arthroplasty: Detailed statistical analysis plan for the RECIPE randomised clinical trial
Study context
- Population
- Patients undergoing planned primary total hip arthroplasty
- Planned comparison
- Combinations of paracetamol, ibuprofen and dexamethasone for pain after total hip arthroplasty
- Primary endpoint
- Total opioid consumption
- Follow-up
- 0-24 h after end of surgery
Methodological detailsblinded, parallel four-group, multicentre, Bonferroni-adjusted alfa 0.0083, pairwise comparisons, Primary analysis in modified ITT population, stratified for site; van Elteren test with Hodges-Lehmann median differences and CIs; binary outcomes by logistic regression, Data analysed by two blinded independent statisticians; abstracts for all possible conclusions written before breaking the blind
- Blinded
- Parallel four-group
- Multicentre
- Bonferroni-adjusted alfa 0.0083
- Pairwise comparisons
- Primary analysis in modified ITT population, stratified for site; van Elteren test with Hodges-Lehmann median differences and CIs; binary outcomes by logistic regression
- Data analysed by two blinded independent statisticians; abstracts for all possible conclusions written before breaking the blind
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
Pain treatment after total hip arthroplasty: Detailed statistical analysis plan for the RECIPE randomised clinical trial. Acta Anaesthesiol Scand. Published 12 January 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →