Perioperative medicine & outcomes
Patient and Operative Factors Predict Risk of Discretionary Prolonged Postoperative Mechanical Ventilation in a Broad Surgical Cohort
Authors' conclusion
DPPMV was uncommon in this broad surgical cohort but could be accurately predicted using readily available patient-specific and operative factors.
Study context
- Population
- Adult surgeries with GA and endotracheal intubation, by services not routinely leaving patients intubated for surgical reasons, January 2018–December 2020
- Participants
- 32,915 cases
- Exposure
- DPPMV vs extubated patients
- DPPMVn = 415
- Outcome
- Incidence and risk factors (prediction) of discretionary prolonged postoperative mechanical ventilation (DPPMV)
Methodological detailssingle-centre, LASSO-regularized logistic regression, multivariable risk model
- Single-centre
- LASSO-regularized logistic regression
- Multivariable risk model
Main finding
As reported in the abstract
Incidence of DPPMV and risk model prediction
DPPMV
1.26%
415
- 12-variable risk model AUC for prediction of DPPMV
- 0.97 (95% CI 0.96-0.97)
Observational data: associations, not effects.
Further findings
Emergency surgery
P < 0.001
Surgery during an existing ICU stay
P < 0.001
Elixhauser comorbidities
- DPPMV more likely to have 20 of the 31 Elixhauser comorbidities (P < .05 for each comparison)
Original publication
Patient and Operative Factors Predict Risk of Discretionary Prolonged Postoperative Mechanical Ventilation in a Broad Surgical Cohort. Anesth Analg. Published 13 October 2022. doi:10.
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