Pediatric anesthesia & critical care
Pediatric Charcot–Marie–Tooth disease and peripheral nerve blocks: a retrospective cohort study of 25 patients
Authors' conclusion
Despite concerns, PNB showed favourable outcomes in a pediatric cohort with CMT disease, with low opioid consumption and pain scores and minimal complications during follow-up.
Study context
- Population
- Pediatric patients with charcot-Marie-Tooth (CMT) disease undergoing orthopedic surgery with peripheral nerve blocks (PNB)
- Participants
- 25 patients
- Outcome
- New neurologic impairments after PNB
Methodological detailssingle-centre, descriptive statistics
- Single-centre
- Descriptive statistics
Main finding
As reported in the abstract
No new neurologic impairments
24 of 25
96%
Nerve injury possibly related to the surgical procedure
1
Observational data: associations, not effects.
Further findings
Pre-existing neurologic deficits (primarily lower extremities)
- Pre-existing neurologic deficits
- 14 (56%)
Opioid consumption · PACU and day of surgery
- Low opioid consumption in the PACU and on the day of surgery
Safety
Additional complications · first 72 hr after surgery
- No additional complications
Original publication
Pediatric Charcot–Marie–Tooth disease and peripheral nerve blocks: a retrospective cohort study of 25 patients. Can J Anaesth. Published 17 September 2024. doi:10. 1007/ s12630-024-02832-z
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