Pediatric anesthesia & critical care

Pediatric Charcot–Marie–Tooth disease and peripheral nerve blocks: a retrospective cohort study of 25 patients

Can J AnaesthPublished Retrospective cohort study

Authors' conclusion

Despite concerns, PNB showed favourable outcomes in a pediatric cohort with CMT disease, with low opioid consumption and pain scores and minimal complications during follow-up.

Study context

Population
Pediatric patients with charcot-Marie-Tooth (CMT) disease undergoing orthopedic surgery with peripheral nerve blocks (PNB)
Participants
25 patients
Outcome
New neurologic impairments after PNB
Methodological detailssingle-centre, descriptive statistics
  • Single-centre
  • Descriptive statistics

Main finding

As reported in the abstract

No new neurologic impairments

24 of 25

96%

Nerve injury possibly related to the surgical procedure

1

Observational data: associations, not effects.

Further findings

Pre-existing neurologic deficits (primarily lower extremities)

Pre-existing neurologic deficits
14 (56%)

Opioid consumption · PACU and day of surgery

Low opioid consumption in the PACU and on the day of surgery

Safety

Additional complications · first 72 hr after surgery

No additional complications

Original publication

Pediatric Charcot–Marie–Tooth disease and peripheral nerve blocks: a retrospective cohort study of 25 patients. Can J Anaesth. Published 17 September 2024. doi:10.1007/s12630-024-02832-z

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