Pediatric anesthesia & critical care
Pediatric Ventilator-Associated Events Before and After a Multicenter Quality Improvement Initiative
Authors' conclusion
This study found that a multicenter quality improvement intervention targeting PedVAE risk factors was associated with a substantial reduction in the rate of PedVAEs in hospital ICUs.
Study context
- Population
- Mechanically ventilated patients in neonatal, pediatric and cardiac intensive care units (ICUs) of 95 hospitals in the Children's Hospitals' Solutions for Patient Safety (SPS) network, North America, 2017–2020
- Participants
- 95 hospitals
- Comparison
- Quality improvement bundle vs no bundle; PedVAE rates before vs after
- Pioneern = 21
- non-Pioneern = 74reference
- Outcome
- PedVAE rates
Methodological detailsbefore-after, Reliable reporters: outcome data submitted for at least 80% of baseline and postbaseline periods; 12 (57%) Pioneer and 33 (45%) non-Pioneer hospitals
- Before-after
- Reliable reporters: outcome data submitted for at least 80% of baseline and postbaseline periods; 12 (57%) Pioneer and 33 (45%) non-Pioneer hospitals
Main finding
As reported in the abstract
PedVAE rate, events per 1000 ventilator days, before vs after bundle
- Among the 12 hospitals, PedVAE rate decreased from 1.9 to 1.4 events per 1000 ventilator days
- No significant change in PedVAE rate among the 33 reliably reporting hospitals that did not implement the bundle
Further findings
| Outcome | Values | Absolute rate difference (95% CI) | P value |
|---|---|---|---|
| PedVAE rate in Pioneer hospitals reliably performing daily discussion of extubation readiness (subgroup)After vs before | Extubation readiness discussion (3 hospitals) 2.6 to 1.2 events per 1000 ventilator days | −1.4 (−1.0 to −1.7) | P < 0.001 |
PedVAE rate in Pioneer hospitals reliably performing daily discussion of extubation readiness (subgroup)
- The other 9 hospitals that did not implement this discussion did not have a decrease
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Pediatric Ventilator-Associated Events Before and After a Multicenter Quality Improvement Initiative. JAMA Netw Open. Published 1 December 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →