Perioperative association between c‐reactive protein, pain catastrophizing and acute pain after total knee arthroplasty: A secondary analysis of two randomised trials
Authors' conclusion
There was no association between the postoperative CRP response and postoperative acute pain or pain catastrophizing in patients undergoing total knee arthroplasty in a well-defined multimodal fast-track regime including preoperative glucocorticoids.
Study context
- Population
- Patients undergoing total knee arthroplasty in a multimodal fast-track regime including preoperative glucocorticoids
- Participants
- 119 patients · 2 RCTs
- Primary endpoint
- Correlation between postoperative CRP increase and acute pain during a well-defined mobilisation
- Follow-up
- 24 and 48 h
Methodological detailscorrelation analysis
- Correlation analysis
Primary result
As reported in the abstract
Correlation of preoperative CRP or postoperative CRP increase with pain
- No correlation between preoperative c-reactive protein (CRP) or postoperative CRP increase and pain at both 24 and 48 h
Further findings
Correlation of CRP with pain, high and low pain catastrophizers (subgroup)
- Analyses similar when separated into high and low pain catastrophizers
Correlation of preoperative CRP or postoperative CRP increase with pain catastrophizing (pain catastrophizing scale)
- No correlation between preoperative CRP or postoperative CRP increase and pain catastrophizing
Original publication
Perioperative association between c‐reactive protein, pain catastrophizing and acute pain after total knee arthroplasty: A secondary analysis of two randomised trials. Acta Anaesthesiol Scand. Published 22 June 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →