Perioperative cefazolin prophylaxis in patients with β-lactam allergy: a quality improvement project
Authors' conclusion
Adaptation of a two-question β-lactam antibiotic allergy assessment tool, along with targeted education, was associated with significantly increased rates of cefazolin use for perioperative prophylaxis in patients with a β-lactam antibiotic allergy label.
Study context
- Population
- Elective surgical patients with a self-reported β-lactam antibiotic allergy (SRBA), University Health Network, Toronto, Canada
- Comparison
- ModACCEPT history-based allergy assessment tool plus targeted education vs pre-intervention baseline
- Outcome
- Proportion of patients with SRBA receiving cefazolin perioperative prophylaxis
Methodological detailsinterrupted time series analysis
- Interrupted time series analysis
Main finding
As reported in the abstract
Cefazolin perioperative prophylaxis rate, primary hospital site
Further findings
Cefazolin use rate, second hospital site
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Perioperative cefazolin prophylaxis in patients with β-lactam allergy: a quality improvement project. Can J Anaesth. Published 7 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →