Perioperative Hemodynamics and Clinical Outcomes of Cesarean Delivery Under Neuraxial Anesthesia in Women with Fontan Circulation: A Single-Center Retrospective Cohort Study
Authors' conclusion
In this cohort of carefully selected patients with Fontan circulation, cesarean delivery was associated with manageable hemodynamic fluctuations and acceptable short-term outcomes when continuous CVP monitoring and timely pharmacologic interventions were implemented.
Study context
- Population
- Women with Fontan circulation undergoing cesarean delivery under neuraxial anesthesia, tertiary referral center in Japan (2009–2025)12 deliveries (11 women)
- Outcome
- Hemodynamic change after neuraxial anesthesia
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Clinically significant hypotension avoided with vasopressor support (deliveries)
11 of 12
Observational data: associations, not effects.
Further findings
Hemodynamic change immediately after delivery
mmHg
- SBP decreased in all cases; estimated paired difference
- −21.0 (95% CI −25.0 to −17.0; p = 0.003)
- Central venous pressure (CVP) no consistent change; estimated paired difference
- 0.0 (95% CI −7.5 to 2.0; p = 0.96)
Safety
Intraoperative new-onset HF or arrhythmias requiring treatment
- None occurred
- 0
Postoperative arrhythmias
- Deliveries with postoperative arrhythmias
- 25%
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
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