Pediatric anesthesia & critical care
Perioperative hypertension and anesthetic management in patients undergoing resection of neuroblastoma
Authors' conclusion
Intraoperative hypertension in patients with neuroblastoma remains a relatively uncommon occurrence; however, it does occur at a frequency higher than previously described.
Study context
- Population
- Children with neuroblastoma undergoing surgical resection, Boston Children's Hospital, July 2012–February 2021
- Participants
- 102 children
- Outcome
- Significant intraoperative hypertension (maximum SBP >95th percentile +12 mmHg based on normative BP data)
Methodological detailssingle-centre
- Single-centre
Main finding
As reported in the abstract
Incidence of intraoperative hypertension
Overall incidence of intraoperative hypertension
13%
n = 13/102
Observational data: associations, not effects.
Further findings
Factors associated with intraoperative hypertension
- Higher American Society of Anesthesiologists (ASA) physical status associated with intraoperative hypertension
Intraoperative antihypertensive medication
- Antihypertensives given intraoperatively
- 9% of cases (n = 9)
- Use significantly associated with intraoperative hypertension
Preoperative urine catecholamines (patients with data)
- Patients with preoperative urine catecholamine data
- 82
- Patients with intraoperative hypertension who had elevated preoperative urine catecholamines
- all 10
Safety
- Intraoperative hypertension not associated with postoperative hypertension, postoperative hypotension or increased ICU LOS
Original publication
Perioperative hypertension and anesthetic management in patients undergoing resection of neuroblastoma. Paediatr Anaesth. Published 13 April 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →