Perioperative medicine & outcomes
Perioperative Iron Deficiency in Patients Scheduled for Major Elective Surgeries: A French Prospective Multicenter Cross-Sectional Study
Authors' conclusion
Iron deficiency was present in half of patients scheduled for major surgery. However, few treatments to correct iron deficiency were implemented preoperatively or postoperatively.
Study context
- Population
- Patients scheduled for major elective orthopedic, cardiac, urologic/abdominal or gynecological surgery in 46 French centers
- Participants
- 1,494 patients · 46 centers
- Outcome
- Prevalence of iron deficiency (serum ferritin <100 µg/L and/or transferrin saturation (TSAT) <20%)
- Follow-up
- D-1/D0
Methodological detailsprospective, multicentre, Patients included from July 20, 2021 to January 3, 2022
- Prospective
- Multicentre
- Patients included from July 20, 2021 to January 3, 2022
Main finding
As reported in the abstract
Prevalence of iron deficiency
Prevalence of iron deficiency
47.0%
95% CI 44.5–49.5
Observational data: associations, not effects.
Further findings
Prevalence of iron deficiency at 30 days after surgery
- Prevalence of iron deficiency
- 45.0% (95% CI 42.0-48.0)
- 1085 patients with available data
Anemia and/or iron deficiency
- Anemia and/or iron deficiency at D-1/D0
- 53.6%
- Anemia and/or iron deficiency at D30 (P < .0001 vs D-1/D0)
- 71.3%
Both anemia and iron deficiency
- Both anemia and iron deficiency at D-1/D0
- 12.2%
- Both anemia and iron deficiency at D30 (P < .0001 vs D-1/D0)
- 32.4%
Treatment of anemia and/or iron deficiency
- Treated preoperatively
- 7.7%
- Treated postoperatively
- 21.7%
- Intravenous iron postoperatively
- 14.2%
Original publication
Perioperative Iron Deficiency in Patients Scheduled for Major Elective Surgeries: A French Prospective Multicenter Cross-Sectional Study. Anesth Analg. Published 7 March 2023. doi:10.
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