Perioperative medicine & outcomes
A perioperative medicine platform trial (PROMPT) evaluating interventions to reduce the risk of infection and other major complications after surgery: rationale and design
Study context
- Population
- Adults undergoing a broad range of surgical procedures in participating hospitals
- Planned comparison
- Interventions to reduce perioperative infection; first domain: liberal inspired oxygen concentrations during surgery
- Primary endpoint
- Incidence of surgical site infection
- Follow-up
- Up to 30 days after index surgery
Methodological detailsrationale and design, multicentre, Protocol version 1.1, December 4, 2025, Secondary outcomes: other health care-associated infections and major postoperative complications up to 30 days, quality of recovery (QoR-15) at 3 and 30 days, DAH30
- Rationale and design
- Multicentre
- Protocol version 1.1, December 4, 2025
- Secondary outcomes: other health care-associated infections and major postoperative complications up to 30 days, QoR-15 at 3 and 30 days, DAH30
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
A perioperative medicine platform trial (PROMPT) evaluating interventions to reduce the risk of infection and other major complications after surgery: rationale and design. BJA Open. Published 28 August 2026. doi:10.
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