Paediatric anaesthesia & critical care
Perioperative monitoring in oesophageal atresia and congenital diaphragmatic hernia patients - exploring the impact of diagnosis on neurocardiovascular coupling
Authors' conclusion
Except for NVC, perioperative connectivity measures do not differ between patients with CDH and OA. Future research should validate these integrative monitoring models in healthy populations and connect them to long-term outcomes, to support development of an interpretable bedside tool for risk stratification and personalized interventions.
Study context
- Population
- Neonates with congenital diaphragmatic hernia (CDH) or oesophageal atresia (OA) who underwent surgical treatment between 2018 and 2022; exclusion of major cardiac or chromosomal anomalies and syndromes associated with major neurodevelopmental impairment
- Exposure
- Effects of anaesthesia and surgery on perioperative cerebral physiology in patients with OA and CDH
- Outcome
- Neurovascular coupling (NVC), intraoperative
- Follow-up
- Intraoperatively
Main finding
As reported in the abstract
- Significantly stronger NVC intraoperatively in CDH patients compared to OA patients
Observational data: associations, not effects.
Further findings
NVC by sevoflurane dosage
- A higher median dosage sevoflurane was associated with weaker NVC
Connectivity measures by surgical technique (open versus minimally invasive)
- Surgical technique did not affect any of the connectivity measures
Original publication
Perioperative monitoring in oesophageal atresia and congenital diaphragmatic hernia patients - exploring the impact of diagnosis on neurocardiovascular coupling. J Clin Monit Comput. Published 8 October 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →