Perioperative medicine & outcomes
Perioperative urinary ketosis and metabolic acidosis in patients fasted for undergoing gynecologic surgery
Authors' conclusion
Perioperative urinary ketosis and intraoperative metabolic acidosis are common in patients undergoing gynecologic surgery, even with short-term preoperative fasting. The risks are notably higher in younger patients with lower body mass index.
Study context
- Population
- Non-diabetic adults undergoing gynecologic surgery under GA after fasting, January–December 2022
- Participants
- 1,831 adults
- Outcome
- Incidence of perioperative urinary ketosis (postoperative urine test)
Main finding
As reported in the abstract
Postoperative ketonuria
Ketonuria among 1535 patients with postoperative urinalysis
912
59.4%
Observational data: associations, not effects.
Further findings
Risk factors for postoperative ketonuria
- Younger age, higher BMI and surgery starting late afternoon were significant risk factors after adjustment
- Patients with ketonuria were younger, had lower BMI and fewer comorbidities
Intraoperative metabolic acidosis (arterial blood gas)
- Metabolic acidosis among 929 patients assessed
- 29.0%
- Perioperative ketonuria and prolonged surgery significantly increased risk of moderate-to-severe metabolic acidosis (multivariable logistic regression)
Original publication
Perioperative urinary ketosis and metabolic acidosis in patients fasted for undergoing gynecologic surgery. Acta Anaesthesiol Scand. Published 6 April 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →