ICU sedation, delirium & recovery
Physical impairment as the dominant component of new-onset post-intensive care syndrome following in-hospital resuscitation
Authors' conclusion
New-onset PICS, driven by physical decline, affects one in six IHCA survivors surviving the first year.
Study context
- Population
- In-hospital cardiac arrest (IHCA) hospital survivors, South Korean National Health Insurance Service database (2013–2023)
- Participants
- 43,331 hospital survivors
- Outcome
- Cumulative incidence of new-onset PICS (ICD-10 coded diagnoses; healthcare utilization-based incidence)
- Follow-up
- 12 months
Methodological detailsadministrative claims database, ICD-10 coded diagnoses
- Administrative claims database
- ICD-10 coded diagnoses
Main finding
As reported in the abstract
Cumulative incidence of new-onset PICS
12-month cumulative incidence of new-onset post-intensive care syndrome (PICS)
6.7%
95% CI 6.5–6.9%
Observational data: associations, not effects.
Further findings
Incidence of new-onset PICS in stable one-year survivors (sensitivity analysis, n = 11,862)
- Incidence of new-onset PICS
- 15.9% (95% CI 15.3-16.6%)
- Physical impairment domain
- 15.0%
- Cognitive domain
- 0.5%
- Psychiatric domain
- 0.8%
- Sensitivity analysis
Predictors of PICS
- ECMO support, OR (P < 0.001)
- 1.44
- Odds of PICS diagnosis in 2022, OR
- 2.19
- Odds of PICS diagnosis in 2023, OR
- 2.12
- Increased length of hospitalization a robust predictor
- Odds of PICS diagnosis significantly escalated from 2021 onwards
Original publication
Physical impairment as the dominant component of new-onset post-intensive care syndrome following in-hospital resuscitation. Resuscitation. Published 10 April 2026. doi:10. 1016/ j. resuscitation. 2026. 111085
Composed by AI from the published abstract and checked against it. How Briefs are made →