ICU sedation, delirium & recovery

Patient versus surrogate decision making for life sustaining treatment and terminal care intensity

Am J Respir Crit Care MedPublished Nationwide population-based cohort study

Authors' conclusion

Surrogate-led decisions were associated with paradoxically higher care intensity and costs, potentially overriding prior patient wishes.

Study context

Population
Adult Intensive Care Unit (ICU) admissions, South Korean National Health Insurance Service database, 2020–2023
Participants
1,189,042 admissions · 417 hospitals
Exposure
Patient-determined vs surrogate-determined Physician Orders for Life-Sustaining Treatment (POLST) vs no documentation
Outcome
Invasive terminal care (among 90-day decedents)
Methodological detailshigh-dimensional fixed-effects models, 417 hospitals
  • High-dimensional fixed-effects models
  • 417 hospitals

Main finding

As reported in the abstract

Invasive terminal care, 90-day decedents
Each group vs no documentationOdds ratio (95% CI)
PD-POLST
0.43(0.43–0.54)
SD-POLST
2.16(1.98–2.35)

Observational data: associations, not effects.

Further findings

OutcomeOR (95% CI)
Invasive terminal care, patients with proactive ADs (subgroup)SD-POLST vs No documentation1.69 (1.51–1.89)
OutcomeCost ratio (95% CI)
Daily hospitalization costsSD-POLST vs No documentation1.04 (1.02–1.06)
  • Invasive terminal care, patients with proactive Advance Directives (ADs) (subgroup): patients with proactive ADs once a surrogate signed the final order
  • Invasive terminal care, patients with proactive ADs (subgroup): 90-day decedents

Invasive terminal care, patients with proactive ADs (subgroup)

Increased care intensity once a surrogate signed the final order ("AD erosion")

Original publication

Patient versus surrogate decision making for life sustaining treatment and terminal care intensity. Am J Respir Crit Care Med. Published 12 June 2026. doi:10.1093/ajrccm/aamag276

Composed by AI from the published abstract and checked against it. How Briefs are made →

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