ICU sedation, delirium & recovery
Post‐intensive care syndrome after critical illness: incidence and predictors in a nationwide cohort
Authors' conclusion
In a nationwide cohort of 234,069 ICU survivors, over half developed PICS within 12 months, with physical impairment most common.
Study context
- Population
- Adults admitted to any ICU in South Korea who were alive ≥ 12 months after hospital discharge, without prior post-intensive care syndrome (PICS) diagnosisno prior PICS diagnosis
- Participants
- 234,069 adults
- Outcome
- Incidence of PICS (new diagnosis in at least one domain - physical, cognitive or psychiatric)
- Follow-up
- Within 12 months of hospital discharge
Methodological detailsnationwide, South Korean National Health Insurance Service database
- Nationwide
- South Korean National Health Insurance Service database
Main finding
As reported in the abstract
PICS incidence
ICU survivors
55.6%
130,110 of 234,069
Observational data: associations, not effects.
Further findings
Risk factors for PICS · within 12 months of hospital discharge
| OR (95% CI) | ||
|---|---|---|
| Older age | 1.01 (1.01–1.01) | |
| Female sex | 1.17 (1.15–1.19) | |
| Lower income (Medical Aid beneficiaries) | 1.16 (1.12–1.21) | |
| Pre-existing disability, mild-to-moderate | 1.12 (1.09–1.15) | |
| Pre-existing disability, severe | 1.08 (1.05–1.12) | |
| Cerebrovascular disease | 1.88 (1.84–1.92) | |
| Dementia | 3.11 (2.91–3.31) | |
| Chronic pulmonary disease | 1.25 (1.22–1.28) | |
| Mechanical ventilation | 1.40 (1.36–1.44) | |
| CRRT | 1.12 (1.05–1.12) | |
| 0.20.5125Odds ratio (log scale) |
Original publication
Post‐intensive care syndrome after critical illness: incidence and predictors in a nationwide cohort. Anaesthesia. Published 23 January 2026. doi:10.
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