Organ support & nutrition

Post-surgical DKA stems from poor glycemic control prior to surgery and perioperative catecholamine usage: unmatched case–control study

Perioper Med (Lond)Published Unmatched case–control study

Main finding · Poor glycemic control (HbA1C ≥7%)Result — go to the resultOdds ratio 48.2 95% CI 12.1–267.4

Authors' conclusion

Post-surgical DKA was ascribed to poor glycemic control. The usage of catecholamine during surgery associated with postsurgical DKA

Study context

Population
Adult post-surgical ICU admissions, King Saud Medical City, Riyadh, Saudi Arabia, March 2019–December 2022
Participants
57 vs 114
Comparison
Post-surgical DKA cases vs post-surgical ICU controls without DKA
  • Casesn = 57
  • Controlsn = 114reference
Outcome
Poor glycemic control before surgery (HbA1C ≥7%)
Methodological detailssingle-centre
  • Single-centre

Main finding

Poor glycemic control (HbA1C ≥7%)

Odds ratio

48.2

95% CI 12.1–267.4

P < 0.001

Cases vs Controls
OR 48.2 (95% CI 12.1–267.4); P < 0.001

As reported in the abstract

Further findings

OutcomeOR (95% CI)P value
Poor glycemic control, age- and sex-matched pairs (sensitivity analysis)54 matched pairs48.6 (12.1–267.4)P < 0.001

Independent predictors of postoperative DKA (multivariable logistic regression)

Intraoperative catecholamine and insulin use and prolonged surgery duration were significant predictors
P < 0.05

Original publication

Post-surgical DKA stems from poor glycemic control prior to surgery and perioperative catecholamine usage: unmatched case–control study. Perioper Med (Lond). Published 28 March 2026. doi:10.1186/s13741-026-00675-4

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