Pediatric anesthesia & critical care
Postanesthesia complications in pediatric patients with previous SARS‐CoV‐2 infection: A cohort study
Main finding · All postanesthesia complications within 30 daysResult — go to the resultRisk difference 19.9 95% CI 4.7–35.1Authors' conclusion
Postanesthesia complications are higher in children who undergo anesthesia within 7 days of SARS-CoV-2 diagnosis.
Study context
- Population
- Pediatric patients undergoing anesthesia, January 3-October 7, 2020matched 1:2
- Participants
- 341 patients
- Comparison
- Previous SARS-CoV-2 infection vs no SARS-CoV-2
- SARS-CoV-2 positiven = 114
- SARS-CoV-2 negativen = 227reference
- Outcome
- Rate of all postanesthesia complications (unplanned escalations of care within 48 h; cardiac, respiratory, thrombotic and hemorrhagic events)
- Follow-up
- 30 days
Methodological detailssingle-centre, matched 1:2 by age and type of procedure
- Single-centre
- Matched 1:2 by age and type of procedure
Main finding
All postanesthesia complications within 30 days
Risk difference
19.9
95% CI 4.7–35.1
P = 0.001
Previous SARS-CoV-2 infection (within 90 days) vs no SARS-CoV-2
risk difference 19.9 (95% CI 4.7–35.1); P = 0.001
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
Hospital LOS
| Risk difference (95% CI) | P value | ||
|---|---|---|---|
| Positive test 0-7 days prior to anesthesia | 7.8 (1.2–14.4) | P < 0.001 | |
| −1001020Difference (linear scale) |
- No increased hospital LOS among SARS-CoV-2 positive patients diagnosed >8 days before anesthetic
30-day mortality
- No deaths within 30 days of anesthetic
Safety
Cardiac complications within 30 days
| Risk difference (95% CI) | P value | ||
|---|---|---|---|
| Anesthesia >42 days from SARS-CoV-2 diagnosis | 4.3 (0.9–10.0) | P = 0.029 | |
| −5051015Difference (linear scale) |
Original publication
Postanesthesia complications in pediatric patients with previous SARS‐CoV‐2 infection: A cohort study. Paediatr Anaesth. Published 7 November 2022. doi:10.
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