Postoperative analgesic consumption for primary versus first repeat Cesarean delivery: a historical cohort study
Main finding · Opioid consumption (OME)Result — go to the resultAdjusted rate ratio 1.20 95% CI 0.95–1.51Authors' conclusion
In this retrospective study, we found no differences in postoperative opioid consumption or reported pain scores in patients who underwent both a primary and a first repeat CD.
Study context
- Population
- Patients who underwent both a primary and a first repeat Cesarean delivery (CD) under neuraxial anesthesia, standardized multimodal analgesia, 1 January 2016 to 30 November 2022each patient in both groups
- Participants
- 409 patients
- Exposure
- First repeat CD vs primary CD in the same patients
- Outcome
- Opioid consumption in oral morphine equivalents (OME)
- Follow-up
- 48 hr after surgery
Methodological detailssingle-centre, same patients as own controls
- Single-centre
- Same patients as own controls
Main finding
Opioid consumption (OME) · 48 hr
Adjusted rate ratio
1.20
95% CI 0.95–1.51
By group
Repeat CD vs Primary CD
adjusted rate ratio 1.20 (95% CI 0.95–1.51)
As reported in the abstract
Observational data: associations, not effects.
Secondary outcomes
AUC for pain scores at 24 and 48 hr, and opioid consumption at 24 hr
- No significant differences between primary and repeat CD (unadjusted)
Original publication
Postoperative analgesic consumption for primary versus first repeat Cesarean delivery: a historical cohort study. Can J Anaesth. Published 17 June 2024. doi:10.
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