Perioperative medicine & outcomes
Postoperative morbidity after suspected grade III perioperative immediate hypersensitivity reactions with completed surgery: a matched case–control study
Main finding · Composite outcomeResult — go to the resultOdds ratio 3.54 95% CI 1.14–11.00Authors' conclusion
Patients with suspected grade III POH whose surgery was completed had a higher incidence of postoperative morbidity than matched controls undergoing similar surgical procedures.
Study context
- Population
- Adults with suspected grade III perioperative immediate hypersensitivity reactions whose surgery was completed, Lille University Hospital, 2012–2023
- Participants
- 35 vs 101
- Exposure
- Cases vs Controls
- Casesn = 35
- Controlsn = 101reference
- Outcome
- Composite:
- 30-day postoperative morbidity
- Mortality
- Follow-up
- 30 days
Methodological detailssingle-centre
- Single-centre
Main finding
Composite outcome
Odds ratio
3.54
95% CI 1.14–11.00
P = 0.029
By group
Cases vs Controls
OR 3.54 (95% CI 1.14–11.00); P = 0.029
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | P value | |
|---|---|---|---|
| Composite outcome (subgroup: documented mast cell activation) | 1.57 (0.24–10.31) | P = 0.64 | |
| 0.050.21520Odds ratio (log scale) |
Original publication
Postoperative morbidity after suspected grade III perioperative immediate hypersensitivity reactions with completed surgery: a matched case–control study. Anaesth Crit Care Pain Med. Published 22 September 2026. doi:10.
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