Perioperative medicine & outcomes

Postoperative nausea and vomiting: translating pathophysiological mechanisms into clinical management

Perioper Med (Lond)Published Narrative review

Study context

Population
Adults undergoing general anesthesia (GA)
Methodological detailsReviews Postoperative Nausea and Vomiting (PONV) mechanisms, patient-, surgery- and anaesthesia-related factors, and pharmacological and non-pharmacological prevention and treatment, Summarises RCTs of PONV incidence with opioid-sparing or opioid-free GA-based protocols
  • Reviews PONV mechanisms, patient-, surgery- and anaesthesia-related factors, and pharmacological and non-pharmacological prevention and treatment
  • Summarises RCTs of PONV incidence with opioid-sparing or opioid-free GA-based protocols

Original publication

Postoperative nausea and vomiting: translating pathophysiological mechanisms into clinical management. Perioper Med (Lond). Published 29 December 2025. doi:10.1186/s13741-025-00626-5

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