Perioperative medicine & outcomes
Postoperative Outcomes Associated with the Timing of Surgery After SARS-CoV-2 Infection
Authors' conclusion
In a contemporary surgical cohort, patients with prior SARS-CoV-2 infection only had increased postoperative mortality or complications when they had surgery within 14 days after the positive test.
Study context
- Population
- Veterans undergoing surgical procedures at US Veterans Health Administration facilities, April 2020 to September 202216,563 (20%) infected
- Participants
- 82,815 veterans
- Exposure
- Within 14 days vs No infection
- Outcome
- 90-day all-cause mortality and 30-day complications
Methodological detailsmatched 1:4 within surgical procedure groupings, multicentre, hierarchical multilevel multivariable logistic regression
- Matched 1:4 within surgical procedure groupings
- Multicentre
- Hierarchical multilevel multivariable logistic regression
Main finding
As reported in the abstract
90-day mortality and 30-day complications
Within 14 days vs No infectionOdds ratio (95% CI)
90-day mortality
1.42(1.08–1.86)
Complications
1.32(1.11–1.57)
Observational data: associations, not effects.
Further findings
| Outcome | OR (95% CI) | |
|---|---|---|
| ASA 4-5 (ASA-stratified models), surgery within 14 daysWithin 14 days vs No infection · 90-day mortality | 1.40 (1.12–1.75) | |
| ASA 4-5 (ASA-stratified models), surgery within 14 daysWithin 14 days vs No infection · complications | 1.73 (1.34–2.24) | |
| 0.512Odds ratio (log scale) |
ASA 4-5 (ASA-stratified models), surgery within 14 days
- Associations confined to ASA 4-5
Original publication
Postoperative Outcomes Associated with the Timing of Surgery After SARS-CoV-2 Infection. Ann Surg. Published 7 February 2024. doi:10.
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