Perioperative medicine & outcomes

Postoperative pulmonary complications in emergency abdominal surgery. A prospective international cohort study

Anaesth Crit Care Pain MedPublished Prospective cohort study

Authors' conclusion

Incidence of PPCs in patients undergoing emergency abdominal surgery is significant. Among the modifiable risk factors, a lack of neuromuscular block reversal and postoperative positive air test were associated with the increased incidence of PPCs.

Study context

Population
Consecutive patients >18 y/o undergoing emergency abdominal surgery, 45 hospitals, 5 geographical areas, April–June 2023
Participants
507 patients · 45 hospitals
Outcome
Incidence of PPCs (acute respiratory failure, pneumothorax, weaning failure, ARDS, pulmonary infection, atelectasis, pleural effusion, bronchospasm, aspiration pneumonitis, pulmonary thromboembolism, pulmonary edema)
Follow-up
First 7 postoperative days
Methodological detailsinternational, multicentre, consecutive patients, 7-day follow-up
  • International
  • Multicentre
  • Consecutive patients
  • 7-day follow-up

Main finding

As reported in the abstract

PPCs incidence

Postoperative pulmonary complications (PPCs): 114 patients

22.5%

Severe PPCs: 38 patients

7.5%

Observational data: associations, not effects.

Further findings

Independent risk factors for PPCs (multivariate analysis)

OR (95% CI)
High ARISCAT scoreMultivariate analysis2.67 (1.06–6.86)
LaparotomyMultivariate analysis2.29 (1.06–5.01)
Postoperative positive air-testMultivariate analysis2.05 (1.02–4.24)
Neuromuscular block reversalAssociated with a reduced risk of PPCs · multivariate analysis0.36 (0.16–0.82)

Original publication

Postoperative pulmonary complications in emergency abdominal surgery. A prospective international cohort study. Anaesth Crit Care Pain Med. Published 22 May 2025. doi:10.1016/j.accpm.2025.101560

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