Perioperative medicine & outcomes
Postoperative Sedation in General Care Wards: A Retrospective Cohort Study
Authors' conclusion
Among patients who met our criteria for PACU discharge, deeper sedation during anesthesia recovery was associated with an increased risk of ward sedation. Patients who had ward sedation had worse outcomes than those without ward sedation.
Study context
- Population
- Adults who underwent procedures with GA at Mayo Clinic, May 5, 2018–December 31, 2020, and were discharged from the postanesthesia care unit (PACU) to the general care wardincluded in analysis
- Participants
- 23,766 adults
- Exposure
- Ward sedation vs Without ward sedation
- Ward sedationn = 1,131
- Outcome
- Ward sedation (RASS ≤−2)
- Follow-up
- Within the first 24 hours after PACU discharge
Methodological detailssingle-centre, multivariable logistic regression
- Single-centre
- Multivariable logistic regression
Main finding
As reported in the abstract
Ward sedation: incidence and association with PACU RASS score
Odds ratio (95% CI)
PACU RASS −1
0.98(0.75–1.27)
PACU RASS −2
1.87(1.44–2.43)
PACU RASS −3
2.98(2.26–3.93)
PACU RASS ≤−4
3.97(2.91–5.42)
- Incidence of ward sedation per 100 patients after GA
- 4.8 (Poisson 95% CI 4.5-5.0)
Observational data: associations, not effects.
Further findings
Timing of ward sedation episodes
- Half of ward sedation episodes occurred within 32 minutes after PACU discharge
Safety
Adverse events requiring an emergency intervention
P < 0.001
Original publication
Postoperative Sedation in General Care Wards: A Retrospective Cohort Study. Anesth Analg. Published 22 July 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →