Cardiac arrest & resuscitation

Potential kidney donors among patients with out-of-hospital cardiac arrest and a termination of resuscitation rule

ResuscitationPublished Prospective registry-based cohort study

Authors' conclusion

Implementing uDCD program including SCD and ECD for kidney transplantation among OHCA cases quickly identified by the TOR, holds significant potential to substantially broaden the pool of organ donors.

Study context

Population
Adults with unexpected of Hospital Cardiac Arrest (OHCA) enrolled in the Parisian registry, May 16th, 2011, to December 31st, 2020resuscitation attempted
Participants
19,976 adults
Outcome
Theoretical size and characteristics of the potential pool of uDCD kidney donors with standard (SCD) and extended criteria (ECD) among patients meeting TOR criteria after OHCA
Methodological detailsParisian registry
  • Parisian registry

Main finding

As reported in the abstract

Potential uDCD kidney donors
No return of spontaneous circulation
64.5% (12,890)
Termination of Resuscitation (TOR) criteria met
47.4% (9,461)
Met standard criteria donation (SCD) criteria (potential organ donors)
8.8% (1,764)
Met extended criteria donation (ECD) for kidney donors
33.6% (6,720)
Mean potential uDCD candidates per year, SCD
98 (±10.8)
Mean potential uDCD candidates per year, ECD
672 (±103.8)

Observational data: associations, not effects.

Further findings

Elderly patients (≥65 y.o.)

Share of patients meeting TOR
61.2% (n = 5,763/9,461)
Share of patients matching both ECD and TOR
100% (5763/5763)

Original publication

Potential kidney donors among patients with out-of-hospital cardiac arrest and a termination of resuscitation rule. Resuscitation. Published 14 July 2024. doi:10.1016/j.resuscitation.2024.110318

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