Neuroanaesthesia & neurocritical care
Potentially Surgical Digestive Complications in Patients With Status Epilepticus: Insights From the ICTAL Registry
Authors' conclusion
Potentially surgical digestive complications in SE were rare but strongly associated with RSE and its treatment. These complications independently predicted hospital mortality.
Study context
- Population
- Adults admitted to ICU for SE, ICTAL Registry, February 2018 to July 2025
- Participants
- 1,007 adults · 23 ICUs
- Exposure
- Digestive complications vs none
- Digestive complicationsn = 16
- Outcome
- Prevalence of digestive complications
Methodological detailsmulticentre (23 ICUs), propensity score, multivariable logistic regression
- Multicentre (23 ICUs)
- Propensity score
- Multivariable logistic regression
Main finding
As reported in the abstract
Digestive complications
1.6%
16
- Onset after SE onset, median (IQR)
- 5 days (3-9 d)
Observational data: associations, not effects.
Further findings
| Outcome | Digestive complications | No digestive complications | OR (95% CI) | P value | |
|---|---|---|---|---|---|
| In-hospital mortality · hospital dischargeIndependent predictor, multivariable logistic regression | 50.0% | 18.4% | 3.43 (1.13–10.21) | P = 0.03 | |
| 0.050.21520Odds ratio (log scale) |
- In-hospital mortality: unadjusted p = 0.005
Surgery among patients with digestive complications
- Surgery required
- 6 (37.5%)
Type of digestive complication
- Paralytic ileus or colonic dilatation
- 13 (81.3%)
- Bowel or colonic ischemia
- 7 (43.8%)
- Median time from SE onset
- 5 days (IQR 3-9 d)
Factors associated with digestive complications
- Refractory SE (RSE) and its treatment (propofol, midazolam, thiopental, ketamine) significantly associated
- Propensity score
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Potentially Surgical Digestive Complications in Patients With Status Epilepticus: Insights From the ICTAL Registry. Crit Care Med. Published 28 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →