Neuroanesthesia & neurocritical care
Electrocardiographic Changes at the Early Stage of Status Epilepticus: First Insights From the ICTAL Registry*
Authors' conclusion
In our study, early ECG abnormalities in the acute phase of SE were frequent, often unrecognized and were associated with clinical and biological stigma of hypoxemia. Although they were not independently associated with 90-day functional outcome
Study context
- Population
- Critically ill adults with SE and an electrocardiogram (ECG) ≤24 hours after SE onset and ≤12 hours after its resolution, 16 ICUs in France, February 2018–June 2020
- Participants
- 155 adults
- Outcome
- Early ECG abnormalities
Methodological detailsdouble-blinded ECG review by two independent cardiologists
- Double-blinded ECG review by two independent cardiologists
Main finding
As reported in the abstract
- Any early ECG abnormality
- 145 (93.5%)
- Major abnormalities among abnormal ECGs
- 91 of 145 (62.8%)
- ST-segment elevation
- 16.6%
- ST-segment depression
- 17.9%
- Negative T waves
- 42.1%
Observational data: associations, not effects.
Further findings
Factors associated with major early ECG abnormalities
- Significantly associated with respiratory distress and sinus tachycardia at the scene and hyperlactatemia at ICU admission
Poor functional outcome (multivariable analysis) · 90 days
- Independently associated: age, preexisting ultimately fatal comorbidity, cerebral insult as cause of SE
- Early major ECG abnormalities not independently associated with 90-day functional outcome
- Multivariable analysis
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Electrocardiographic Changes at the Early Stage of Status Epilepticus: First Insights From the ICTAL Registry*. Crit Care Med. Published 19 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →