Perioperative medicine & outcomes
Pre‐ and Postoperative N‐Terminal Pro B‐Type Natriuretic Peptide Dynamics and Outcomes After Emergency Laparotomy
Authors' conclusion
Preoperative and postoperative N-terminal pro B-type natriuretic peptide concentrations were associated with 90-day mortality in patients undergoing emergency laparotomy.
Study context
- Population
- Patients undergoing emergency laparotomy
- Participants
- 249 patients
- Exposure
- Preoperative and postoperative NT-proBNP concentrations (per doubling) and 90-day mortality
- Outcome
- 90-day mortality
- Follow-up
- 90 days
Methodological detailsexploratory, prospectively registered data
- Exploratory
- Prospectively registered data
Main finding
As reported in the abstract
90-day mortality, odds per doubling of NT-proBNP concentration
Odds ratio (95% CI)
Preoperative
1.89(1.49–2.40)
Postoperative
2.29(1.71–3.06)
Per doubling, as printed
Observational data: associations, not effects.
Further findings
Internally derived threshold-based analyses
- Similar directional pattern
- Exploratory
Perioperative NT-proBNP patterns
- Elevated preoperative but lower postoperative NT-proBNP: lower observed mortality vs persistently elevated concentrations
- Exploratory
Original publication
Pre‐ and Postoperative N‐Terminal Pro B‐Type Natriuretic Peptide Dynamics and Outcomes After Emergency Laparotomy. Acta Anaesthesiol Scand. Published 13 May 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →