Paediatric anaesthesia & critical care

Precision of neuromuscular monitoring in paediatric patients: a randomised prospective agreement study of kinemyography and electromyography

Br J AnaesthPublished Randomised prospective agreement study

Primary result · Repeatability coefficient of TOF ratioResult — go to the resultMedian difference 0.00 95% CI −0.01 to 0.01

Authors' conclusion

Neither kinemyography nor electromyography was inferior to the other in terms of precision.

Study context

Population
Children <5 yr of age stratified into neonates, infants, toddlers and children (2–5 yr)
Participants
64 children
Comparison
Kinemyography vs electromyography
Primary endpoint
Precision of TOF ratios (repeatability coefficient; lower = higher precision) before rocuronium and after assumed complete recovery (after sugammadex)
Methodological detailscontralateral arms
  • Contralateral arms

Primary result

Repeatability coefficient of TOF ratio · baseline (before rocuronium)

Median difference

0.00

95% CI −0.01 to 0.01

By group

Kinemyography

0.06

median · IQR 0.03–0.10

Electromyography

0.06

median · IQR 0.05–0.09

Kinemyography vs Electromyography
median difference 0.00 (95% CI −0.01 to 0.01)

As reported in the abstract

Further findings

OutcomeMedian difference (CI)
Kinemyography repeatability coefficient, non-certified (<5 kg) vs certified (≥5 kg) use (subgroup)Precision worse in non-certified use0.04 (0.02–0.05)
Electromyography repeatability coefficient, neonates vs others (subgroup)Performed similarly regardless of certification−0.01 (−0.04 to 0.05)

TOF ratios <0.9

P < 0.05

Median

OutcomeKinemyographyElectromyography
Repeatability coefficient of TOF ratio after recovery (primary endpoint, second time point) · after recovery (after sugammadex)0.04 (IQR 0.02–0.07)0.04 (IQR 0.03–0.06)
  • Kinemyography repeatability coefficient, non-certified (<5 kg) vs certified (≥5 kg) use (subgroup): <5 kg 0.08 (IQR 0.05–0.11)
  • Kinemyography repeatability coefficient, non-certified (<5 kg) vs certified (≥5 kg) use (subgroup): ≥5 kg 0.04 (IQR 0.02–0.06)
  • Electromyography repeatability coefficient, neonates vs others (subgroup): neonates 0.05 (IQR 0.03–0.11)
  • Electromyography repeatability coefficient, neonates vs others (subgroup): others 0.06 (IQR 0.03–0.09)

Original publication

Precision of neuromuscular monitoring in paediatric patients: a randomised prospective agreement study of kinemyography and electromyography. Br J Anaesth. Published 31 July 2026. doi:10.1016/j.bja.2026.06.016

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