Paediatric anaesthesia & critical care
Precision of neuromuscular monitoring in paediatric patients: a randomised prospective agreement study of kinemyography and electromyography
Primary result · Repeatability coefficient of TOF ratioResult — go to the resultMedian difference 0.00 95% CI −0.01 to 0.01Authors' conclusion
Neither kinemyography nor electromyography was inferior to the other in terms of precision.
Study context
- Population
- Children <5 yr of age stratified into neonates, infants, toddlers and children (2–5 yr)
- Participants
- 64 children
- Comparison
- Kinemyography vs electromyography
- Primary endpoint
- Precision of TOF ratios (repeatability coefficient; lower = higher precision) before rocuronium and after assumed complete recovery (after sugammadex)
Methodological detailscontralateral arms
- Contralateral arms
Primary result
Repeatability coefficient of TOF ratio · baseline (before rocuronium)
Median difference
0.00
95% CI −0.01 to 0.01
By group
Kinemyography
0.06
median · IQR 0.03–0.10
Electromyography
0.06
median · IQR 0.05–0.09
Kinemyography vs Electromyography
median difference 0.00 (95% CI −0.01 to 0.01)
As reported in the abstract
Further findings
| Outcome | Median difference (CI) | |
|---|---|---|
| Kinemyography repeatability coefficient, non-certified (<5 kg) vs certified (≥5 kg) use (subgroup)Precision worse in non-certified use | 0.04 (0.02–0.05) | |
| Electromyography repeatability coefficient, neonates vs others (subgroup)Performed similarly regardless of certification | −0.01 (−0.04 to 0.05) | |
| −0.06−0.04−0.0200.020.040.06Difference (linear scale) |
TOF ratios <0.9
P < 0.05
Median
| Outcome | Kinemyography | Electromyography |
|---|---|---|
| Repeatability coefficient of TOF ratio after recovery (primary endpoint, second time point) · after recovery (after sugammadex) | 0.04 (IQR 0.02–0.07) | 0.04 (IQR 0.03–0.06) |
- Kinemyography repeatability coefficient, non-certified (<5 kg) vs certified (≥5 kg) use (subgroup): <5 kg 0.08 (IQR 0.05–0.11)
- Kinemyography repeatability coefficient, non-certified (<5 kg) vs certified (≥5 kg) use (subgroup): ≥5 kg 0.04 (IQR 0.02–0.06)
- Electromyography repeatability coefficient, neonates vs others (subgroup): neonates 0.05 (IQR 0.03–0.11)
- Electromyography repeatability coefficient, neonates vs others (subgroup): others 0.06 (IQR 0.03–0.09)
Original publication
Precision of neuromuscular monitoring in paediatric patients: a randomised prospective agreement study of kinemyography and electromyography. Br J Anaesth. Published 31 July 2026. doi:10. 1016/ j. bja. 2026. 06. 016
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