Perioperative medicine & outcomes

Predicting deep vein thrombosis risk in patients with knee fractures: a nomogram-based study

Perioper Med (Lond)Published Prediction model development and validation study

Authors' conclusion

The nomogram developed in this study shows intense discrimination, calibration, and clinical utility, suggesting promise for predicting lower extremity DVT and functioning as a quantitative instrument in clinical settings.

Study context

Population
Hospitalised patients with knee fractures
Participants
923 patients
Outcome
Lower limb deep vein thrombosis (DVT) (nomogram discrimination, AUC)
Methodological detailsnomogram, multiple logistic regression, random 7:3 split into training and validation cohorts
  • Nomogram
  • Multiple logistic regression
  • Random 7:3 split into training and validation cohorts

Performance

As reported in the abstract

Discrimination for lower extremity DVT
Test or modelAUC95% CI
Training set0.750.71-0.79
Validation set0.76

AUC

Training set0.75
Validation set0.76

95% CI

Training set0.71-0.79
Validation set— not stated in the abstract
Independent predictors (from 21 variables): age, PTA, FIB, TT, D-dimer, BMI
6

Further findings

Clinical utility (decision curve analysis)

Decision curve analysis confirmed the nomogram's clinical applicability

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Predicting deep vein thrombosis risk in patients with knee fractures: a nomogram-based study. Perioper Med (Lond). Published 30 January 2026. doi:10.1186/s13741-026-00653-w

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