Perioperative medicine & outcomes

Predicting surgical intensive care unit readmission with machine learning model: Bi-center training and validation

J Crit CarePublished Retrospective prognostic model development and validation study

Authors' conclusion

Machine learning models offer greater accuracy and reliability compared to traditional regression methods when predicting SICU readmission.

Study context

Population
Adults admitted to the surgical ICU, Chang Gung Memorial Hospital (development: Kaohsiung, July 2020–December 2022; external validation: Linkou, January 2023–August 2023)development cohorts
Participants
982 adults
Comparison
Gradient Boosting (GB) vs Published traditional logistic regression methods
Outcome
SICU readmission
Methodological detailsmachine learning, bi-centre, external validation
  • Machine learning
  • Bi-centre
  • External validation

Performance

As reported in the abstract

Discrimination for SICU readmission (AUROC), internal validation
Test or modelAUROC
GB0.82 (95% CI: 0.70-0.93)

GB

AUROC0.82 (95% CI: 0.70-0.93)

Further findings

OutcomeGB
Discrimination (AUROC) in the external validation cohort, GB vs three previously published traditional LR methodsExternal validation cohort (Linkou branch)
AUROC0.80
  • Discrimination (AUROC) in the external validation cohort, GB vs three previously published traditional Logistic Regression (LR) methods: Published LR method (first) 0.73 (95% CI 0.63–0.83) · AUROC 0.73
  • Discrimination (AUROC) in the external validation cohort, GB vs three previously published traditional LR methods: Published LR method (second) 0.70 (95% CI 0.60–0.79) · AUROC 0.70
  • Discrimination (AUROC) in the external validation cohort, GB vs three previously published traditional LR methods: Published LR method (third) 0.65 (95% CI 0.50–0.73) · AUROC 0.65

Important features for surgical intensive care unit (SICU) readmission

11 features significantly influenced SICU readmission; top four: central venous catheter usage days, pre-ICU stay duration, blood urea nitrogen, carbapenem usage days

Discrimination (AUROC) in the external validation cohort, GB vs three previously published traditional LR methods

GB model surpassed the three previously published traditional LR methods

Original publication

Predicting surgical intensive care unit readmission with machine learning model: Bi-center training and validation. J Crit Care. Published 19 February 2026. doi:10.1016/j.jcrc.2026.155487

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