Pediatric anesthesia & critical care

Predictors and outcomes of perioperative cardiac arrest in children undergoing noncardiac surgery

BJA OpenPublished Retrospective cohort study

Authors' conclusion

The incidence of cardiac arrest in this study is higher than previously reported.

Study context

Population
Children <18 yr undergoing noncardiac surgery, National Surgical Quality Improvement Program (NSQIP) Pediatric Database 2019 and 2020
Participants
261,276 children
Outcome
Perioperative cardiac arrest (incidence and risk factors)
Methodological detailsregistry database (NSQIP Pediatric 2019 and 2020), exploratory multivariable analysis
  • Registry database (NSQIP Pediatric 2019 and 2020)
  • Exploratory multivariable analysis

Main finding

As reported in the abstract

Perioperative cardiac arrest
Overall rate of cardiac arrest
0.1%
Intraoperative rate
0.05%
48-h postoperative rate
0.06%
Age <12 months, aOR (P<0.001)
3.07
ASA-PS 3, aOR (P<0.001)
2.57
ASA-PS 4, aOR (P<0.001)
5.27
ASA-PS 5, aOR (P<0.001)
13.1
Admission through ED, aOR (P=0.003)
1.7
Inpatient, aOR (P=0.008)
2.19
Major and severe cardiac disease, aOR (P=0.008)
1.58
Impaired cognitive status, aOR (P=0.009)
1.54
Longer anaesthesia duration, aOR per 30 min (P<0.001)
1.1

Observational data: associations, not effects.

Further findings

Outcomes associated with perioperative cardiac arrest

Cardiac arrest significantly associated with longer hospital LOS, reoperation, differences in discharge destination, and 30-day mortality

In-hospital and 30-day mortality, postoperative vs intraoperative cardiac arrest

Significantly higher in-hospital and 30-day mortality after postoperative than intraoperative cardiac arrest

Original publication

Predictors and outcomes of perioperative cardiac arrest in children undergoing noncardiac surgery. BJA Open. Published 3 December 2023. doi:10.1016/j.bjao.2023.100244

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