Pediatric anesthesia & critical care
Point‐of‐care ultrasonography to predict fluid responsiveness in children: A systematic review and meta‐analysis
Authors' conclusion
POCUS has the potential to accurately predict fluid responsiveness in children. However, only ∆Vpeak was found to be a reliable predictor.
Study context
- Population
- Children receiving a fluid challenge (93.4% mechanically ventilated)
- Participants
- 1,028 children · 23 studies
- Comparison
- Ultrasonographic predictors of fluid responsiveness
- Outcome
- Accuracy of ultrasound-based predictors of fluid responsiveness in children
Methodological detailsDatabases searched through July 2022
- Databases searched through July 2022
Pooled result
As reported in the abstract
Pooled accuracy for fluid responsiveness
| Group | Sensitivity | Specificity | AUSROC |
|---|---|---|---|
| ∆Vpeak | 0.84 (95% CI, 0.76-0.90) | 0.82 (95% CI, 0.75-0.87) | 0.89 (95% CI, 0.86-0.92) |
| ∆IVC | 0.79 (95% CI, 0.62-0.90) | 0.70 (95% CI, 0.51-0.84) | 0.81 (95% CI, 0.78-0.85) |
Sensitivity
∆Vpeak0.84 (95% CI, 0.76-0.90)
∆IVC0.79 (95% CI, 0.62-0.90)
Specificity
∆Vpeak0.82 (95% CI, 0.75-0.87)
∆IVC0.70 (95% CI, 0.51-0.84)
AUSROC
∆Vpeak0.89 (95% CI, 0.86-0.92)
∆IVC0.81 (95% CI, 0.78-0.85)
Further pooled results
Positive response to fluid infusion
- Fluid responders
- 59.7%
Original publication
Point‐of‐care ultrasonography to predict fluid responsiveness in children: A systematic review and meta‐analysis. Paediatr Anaesth. Published 19 October 2022. doi:10.
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