Cardiac arrest & resuscitation

Prehospital prognostication after out-of-hospital cardiac arrest in tertiary care centers: the R-EDByUS score in the JAAM-OHCA registry

ResuscitationPublished external validation of a prediction score

Authors' conclusion

The R-EDByUS score showed good discrimination in the JAAM-OHCA Registry, supporting its use for early risk stratification in cardiogenic OHCA even in tertiary care centers.

Study context

Population
Adult patients with presumed cardiogenic out-of-hospital cardiac arrest transported to tertiary care centers, JAAM-OHCA Registrypatients analyzed · prehospital return of spontaneous circulation (ROSC) cohort 3,305 · ongoing cardiopulmonary resuscitation (CPR) cohort 26,040
Participants
29,345 patients
Comparison
R-EDByUS score predictions of unfavorable neurological outcome (Cerebral Performance Category 3-5) at 1 month
  • Prehospital ROSC cohortn = 3,305
  • Ongoing CPR cohortn = 26,040
Outcome
Discrimination for unfavorable neurological outcome (Cerebral Performance Category 3-5)
Follow-up
1 month
Methodological detailsregistry-based
  • Registry-based

Performance

As reported in the abstract

Areas under the curve

0.906 and 0.913

Further findings

Unfavorable outcomes among patients with a predicted probability ≥99%

Calibration

Good calibration in the prehospital ROSC cohort

Discrimination across in-hospital intervention subgroups (subgroup)

Discrimination was lower among patients who received PCI, TTM, or ECMO in the ongoing CPR cohort

Original publication

Prehospital prognostication after out-of-hospital cardiac arrest in tertiary care centers: the R-EDByUS score in the JAAM-OHCA registry. Resuscitation. Published 6 October 2026. doi:10.1016/j.resuscitation.2026.111341

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