Organ support & nutrition

Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit

J Intensive CarePublished Pre-post intervention study

Authors' conclusion

The Sharesource Connect system could be used for the monitoring, collection, and analysis of CRRT data to assist in the QC management related to CRRT

Study context

Population
Patients on continuous renal replacement therapy (CRRT) (9 Prismaflex machines) in three ICUs of a tertiary hospital in Shanghai798 and 717 filters analysed
Exposure
After (2024) vs before (2023) implementing the Sharesource Connect system with a quality improvement program
Outcome
Filter lifespan, downtime percentage, delivered/prescribed dose ratio, ultrafiltration volume, and vascular access alarms
Methodological detailssingle-centre, three ICUs, retrospective 2023 and prospective 2024 data collection, quality improvement program
  • Single-centre
  • Three ICUs
  • Retrospective 2023 and prospective 2024 data collection
  • Quality improvement program

Main finding

As reported in the abstract

Filter lifespan

P = 0.043

Observational data: associations, not effects.

Further findings

Cumulative filter survival · 12 h

difference + 18.1%

Cumulative filter survival · 24 h

difference + 3.7%

Cumulative filter survival · 36 h

difference + 8.0%

Filter survival (Kaplan-Meier)

Improved filter survival, Log-Rank
P < 0.001

Delivered dose

Mean delivered dose (mL/kg/h)
35.67 ± 4.01
Prescribed dose (mL/kg/h)
41.33 ± 4.5

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Preliminary application of the Sharesource connect data collection and analysis system in the management of continuous renal replacement therapy in the intensive care unit. J Intensive Care. Published 18 August 2025. doi:10.1186/s40560-025-00818-7

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