Pediatric anesthesia & critical care
Preoperative anxiety level is not associated with postoperative negative behavioral changes in premedicated children
Authors' conclusion
Based on the findings from this cohort, high preinduction anxiety does not appear to be associated with NBCs postoperatively in children premedicated with clonidine or midazolam.
Study context
- Population
- Children aged 2–7 years undergoing outpatient surgery, premedicated with clonidine or midazolam
- Participants
- 115 children
- Comparison
- High vs low preinduction anxiety (modified Yale Preoperative Anxiety Scale (mYPAS) >30) in children premedicated with clonidine or midazolam
- High preinduction anxietyn = 54
- Primary endpoint
- Association between preoperative anxiety (mYPAS) and postoperative negative behavioral changes (NBCs; >3 on Post Hospital Behavior Questionnaire (PHBQ))
- Follow-up
- 1 week after surgery
Methodological detailsplanned secondary analysis
- Planned secondary analysis
Primary result
As reported in the abstract
Postoperative NBCs (>3) and association with high preinduction anxiety
- Developed >3 postoperative negative behavioral changes (NBCs), of 115
- 19
- Both high preinduction anxiety and >3 NBCs, of 19
- 10
- No association between preinduction anxiety (mYPAS scores) and postoperative NBCs
- p = .62
Further findings
Association of anxiety with NBCs at 4 and 26 weeks · 4- or 26-weeks post-surgery
- No association
Other participant and preoperative factors
- Only lower age associated with development of NBCs
Original publication
Preoperative anxiety level is not associated with postoperative negative behavioral changes in premedicated children. Acta Anaesthesiol Scand. Published 30 March 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →