Respiratory failure & ventilation

Preoperative Atelectasis in Patients with Obesity Undergoing Bariatric Surgery: A Cross-Sectional Study

Anesth AnalgPublished Cross-sectional study

Authors' conclusion

The prevalence and extension of atelectasis increased with higher BMI, being significantly higher at BMI ≥45 kg/m 2 . Preoperative atelectasis mediated the effect of BMI on Sp o2 at room air in the seated position.

Study context

Population
Patients with obesity undergoing laparoscopic bariatric surgery; preoperative chest CT
Participants
236 patients
Exposure
Body mass index (BMI) categories
Outcome
Prevalence of preoperative atelectasis (≥2.5% of total lung volume on CT)
Follow-up
Preoperative
Methodological detailssingle-centre
  • Single-centre

Main finding

As reported in the abstract

Prevalence of atelectasis (overall 32.6%, 95% CI 27.0-38.9)
Each group vs 30 to 35 kg/m 2Adjusted prevalence ratio (95% CI)
45 to 50 kg/m 2E-value lower bound: 2.64
3.52(1.63–7.61)
≥50 kg/m 2E-value lower bound: 7.91
8.0(4.22–15.2)

Observational data: associations, not effects.

Further findings

OutcomeaOR (95% CI)
Odds of greater atelectasis percentage coverage45 to 50 kg/m 2 vs 30 to 35 kg/m 27.5 (2.7–20.9)
Odds of greater atelectasis percentage coverage≥50 kg/m 2 vs 30 to 35 kg/m 291.5 (30.0–279.3)

Variation in preoperative SpO2 explained by atelectasis percent

Variation in preoperative SpO2 explained by atelectasis percent alone
70.2%

Proportion of effect of BMI on preoperative SpO2 <96% mediated through atelectasis

Proportion mediated
81.5% (95% CI, 56.0-100)
  • Inverse probability weighting

Original publication

Preoperative Atelectasis in Patients with Obesity Undergoing Bariatric Surgery: A Cross-Sectional Study. Anesth Analg. Published 23 August 2024. doi:10.1213/ane.0000000000007166

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