Perioperative medicine & outcomes
Preoperative fasting glucose value can predict acute kidney injury in non-cardiac surgical patients without diabetes but not in patients with diabetes
Main finding · Postoperative AKIResult — go to the resultOdds ratio 1.312 95% CI 1.028–1.675Authors' conclusion
A preoperative fasting glucose value of 5.39 mmol/L can predict postoperative acute kidney injury after non-cardiac surgery in patients without diagnosed diabetes, but it is not related to AKI in patients with the diagnosis.
Study context
- Population
- Patients undergoing non-cardiac surgery, Chongqing University Cancer Hospital, January 1, 2017, to May 31, 2023included in final analysis
- Participants
- 39,986 patients
- Exposure
- With DM vs Without DM
- Outcome
- Postoperative AKI (primary exposure: preoperative glucose value)
Methodological detailssingle-centre
- Single-centre
Main finding
Postoperative AKI
Odds ratio
1.312
95% CI 1.028–1.675
P = 0.029
Events by group
With DM vs Without DM
OR 1.312 (95% CI 1.028–1.675); P = 0.029
As reported in the abstract
- Acute kidney injury (AKI) overall
- 741(1.9%)
Observational data: associations, not effects.
Further findings
Optimal cut-point of preoperative fasting glucose to predict AKI (cohort without DM)
| Adjusted OR (95% CI) | P value | ||
|---|---|---|---|
| Optimal cut-point 5.39 mmol/L | 1.802 (1.513–2.146) | P = 0.000 | |
| 0.512Adjusted odds ratio (log scale) |
- Optimal cut-point of preoperative fasting glucose to predict AKI (cohort without DM) — Optimal cut-point of preoperative fasting glucose to predict AKI
- 5.39 mmol/L
Preoperative glucose and AKI (cohort with DM)
- Relation not significant after covariable adjustment
- P = 0.437
AKI risk over the range of preoperative glucose, between cohorts
- No significant difference between cohorts with and without DM
Original publication
Preoperative fasting glucose value can predict acute kidney injury in non-cardiac surgical patients without diabetes but not in patients with diabetes. Perioper Med (Lond). Published 13 May 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →