Pain medicine

Preoperative Patient Education on Opioid Use and Pain After Surgery: A Randomized Trial

Ann SurgPublished Randomised controlled trial

Primary result · Opioid consumptionResult — go to the resultAdjusted ratio of geometric means 1.01 95% CI 0.86–1.18

Authors' conclusion

Preoperative analgesic education did not result in clinically meaningful reductions in opioid consumption or improvements in pain management outcomes.

Study context

Population
Adults scheduled for hip arthroplasty or laparoscopic-assisted abdominal surgery, ASA 1 to 4, without prolonged opioid use, planned regional block or epidural analgesia, or limited English fluencyanalysed
Participants
957 adults
Comparison
Analgesic education vs Generic video
Primary endpoint
Opioid consumption
Follow-up
Initial 72 postoperative hours
Methodological detailssingle-centre, Cleveland Clinic Main Campus, October 2021 to October 2023
  • Single-centre
  • Cleveland Clinic Main Campus, October 2021 to October 2023

Primary result

As reported in the abstract

72 h postoperatively

Adjusted ratio of geometric means

1.01

95% CI 0.86–1.18

P = 0.890

Analgesic education vs Generic video
adjusted ratio of geometric means 1.01 (95% CI 0.86–1.18); P = 0.890

Secondary outcomes

OutcomeAdjusted mean difference (95% CI)P value
Time-weighted average pain scores−0.1 (−0.3 to 0.2)P = 0.617
Patient satisfaction with analgesia−0.1 (−0.3 to 0.2)P = 0.611

Original publication

Preoperative Patient Education on Opioid Use and Pain After Surgery: A Randomized Trial. Ann Surg. Published 14 April 2025. doi:10.1097/sla.0000000000006717

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