Preoperative Patient Education on Opioid Use and Pain After Surgery: A Randomized Trial
Primary result · Opioid consumptionResult — go to the resultAdjusted ratio of geometric means 1.01 95% CI 0.86–1.18Authors' conclusion
Preoperative analgesic education did not result in clinically meaningful reductions in opioid consumption or improvements in pain management outcomes.
Study context
- Population
- Adults scheduled for hip arthroplasty or laparoscopic-assisted abdominal surgery, ASA 1 to 4, without prolonged opioid use, planned regional block or epidural analgesia, or limited English fluencyanalysed
- Participants
- 957 adults
- Comparison
- Analgesic education vs Generic video
- Primary endpoint
- Opioid consumption
- Follow-up
- Initial 72 postoperative hours
Methodological detailssingle-centre, Cleveland Clinic Main Campus, October 2021 to October 2023
- Single-centre
- Cleveland Clinic Main Campus, October 2021 to October 2023
Primary result
As reported in the abstract
72 h postoperatively
Adjusted ratio of geometric means
1.01
95% CI 0.86–1.18
P = 0.890
Analgesic education vs Generic video
adjusted ratio of geometric means 1.01 (95% CI 0.86–1.18); P = 0.890
Secondary outcomes
| Outcome | Adjusted mean difference (95% CI) | P value | |
|---|---|---|---|
| Time-weighted average pain scores | −0.1 (−0.3 to 0.2) | P = 0.617 | |
| Patient satisfaction with analgesia | −0.1 (−0.3 to 0.2) | P = 0.611 | |
| −0.4−0.200.20.4Difference (linear scale) |
Original publication
Preoperative Patient Education on Opioid Use and Pain After Surgery: A Randomized Trial. Ann Surg. Published 14 April 2025. doi:10. 1097/ sla. 0000000000006717
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